Improvement in left ventricular wall motion following nitroglycerin.

Improvement in left ventricular wall motion following nitroglycerin.

Coronary artery disease patients frequently have left ventricular wall motion abnormalities. Though nitroglycerin is commonly used in ischemic heart disease, its effects on wall motion abnormalities is unknown. In this study we have evaluated the effects of nitroglycerin on wall motion abnormalities and on ejection fraction in 25 patients. Sixteen had coronary artery disease (greater than 70% l...

Left Ventricular Wall Motion

The effects of sublingual nitroglycerin (GTN) on left ventricular wall motion (LVWM) were examined by angiographic assessment in eight patients with anginal chest pain. Five of seven patients having occlusive coronary artery disease showed segmental abnormalities in LVWM characterized by regional hypokinesis or akinesis at rest. These abnormalities were accentuated by tachycardia induced by atr...

Left Ventricular Wall Motion

The effects of sublingual nitroglycerin (GTN) on left ventricular wall motion (LVWM) were examined by angiographic assessment in eight patients with anginal chest pain. Five of seven patients having occlusive coronary artery disease showed segmental abnormalities in LVWM characterized by regional hypokinesis or akinesis at rest. These abnormalities were accentuated by tachycardia induced by atr...

Restoration of regional wall motion by nitroglycerin therapy in patients with left ventricular asynergy.

Abnormalities in regional wall motion are not uniformly improved following aortocoronary bypass operation. This study demonstrates that regional wan motion abnormalities may be reversed with nitroglycerin therapy. Eighteen asynergic regions in seven patients with coronary artery &ease were studied before and after sublingually administered nitroglycerin. Although none of the normal areas became...

Effects of nitroglycerin on left ventricular wall motion in coronary artery disease.